Gestational vitamin D deficiency and autism spectrum disorder

Gestational vitamin D deficiency and autism spectrum disorder

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Background There is growing interest in linking vitamin D deficiency with autism spectrum disorders (ASDs).The association between vitamin D deficiency during gestation, a critical period in neurodevelopment, and ASD is not well understood.Aims To determine the association between gestational vitamin D status and telemarkskongen flue ASD.

Method Based on a birth cohort (n=4334), we examined the association between 25-hydroxyvitamin D (25OHD), assessed from both maternal mid-gestation sera and neonatal sera, and ASD (defined by clinical records; n=68 cases).Results Individuals in the 25OHD-deficient group at mid-gestation had more than twofold increased risk of ASD (odds ratio (OR)=2.42, 95% confidence interval (CI) 1.

09 to 5.07, P=0.03) compared with the sufficient group.

The findings persisted in analyses including children of European ethnicity only.Conclusions Mid-gestational vitamin D deficiency luau thank you cards was associated with an increased risk of ASD.Because gestational vitamin D deficiency is readily preventable with safe, inexpensive and readily available supplementation, this risk factor warrants closer scrutiny.